Ezrin (phospho Tyr353) Antibody
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產品名稱: Ezrin (phospho Tyr353) Antibody
產品型號:
產品展商: immunoclone
產品文檔: 無相關文檔
簡單介紹
Ezrin (phospho Tyr353) Antibody迅速增長的產品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Ezrin (phospho Tyr353) Antibody嚴格的質量控制和驗證實驗包括各種不同的應用：WB、細胞**熒光、**組化、流式細胞術、ELISA、CHIP、IP和peptide array。
Ezrin (phospho Tyr353) Antibody
的詳細介紹
Ezrin (phospho Tyr353) AntibodyProduct Profile
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Product Name
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Ezrin (phospho Tyr353) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.1) Zhao H, et al. (2004) Proc Natl Acad Sci U S A101 (25): 9485-9490. Wang Q, et al. (2003) J Biol Chem 278 (48): 47731-47743. Gautreau A, et al. (1999) Proc Natl Acad Sci U S A 96 (13): 7300-7305. Crepaldi T, et al. (1997) J Cell Biol 138 (2): 423-34.
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Immunogen
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Ezrin (Phospho-Tyr353) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 353 (Q-D-Y (p) -E-E) derived from Human EZRIN.
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Ezrin (phospho Tyr353) AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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IHCWB
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Species Reactivity
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HumanMouse
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Ezrin (phospho Tyr353) AntibodyTarget Information
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Gene Symbol
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EZR
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Alternative Names
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CVL
CVIL
VIL2
HEL-S-105
ESR
NR3A1
Cytovillin
EZRI
Villin 2
p81
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Molecular Weight(MW)
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81 kDa
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Tissue Specificity
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This antibody detects endogenous level of Ezrin only when phosphorylated at tyrosine 353.
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Ezrin (phospho Tyr353) AntibodyDatabase Links
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Entrez Gene
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7430
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Protein Accession
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NP_001104547.1
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Ezrin (phospho Tyr353) AntibodyApplication
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Application
Western blot analysis of lysed extracts from 293 cells untreated or treated with EGF using Ezrin (Phospho-Tyr353).
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Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Ezrin (Phospho-Tyr353).
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Application Notes
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Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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