Ezrin (phospho Tyr478) Antibody
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產品名稱: Ezrin (phospho Tyr478) Antibody
產品型號:
產品展商: immunoclone
產品文檔: 無相關文檔
簡單介紹
Ezrin (phospho Tyr478) Antibody迅速增長的產品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Ezrin (phospho Tyr478) Antibody嚴格的質量控制和驗證實驗包括各種不同的應用：WB、細胞**熒光、**組化、流式細胞術、ELISA、CHIP、IP和peptide array。
Ezrin (phospho Tyr478) Antibody
的詳細介紹
Ezrin (phospho Tyr478) AntibodyProduct Profile
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Product Name
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Ezrin (phospho Tyr478) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.1) Murchie R, et al. (2014) Proc Natl Acad Sci U S A 111, 693-8 . Mak H, et al. (2012)BMC Cancer 12, 82. Heiska L, et al. (2011)Oncogene 30, 4953-62 .
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Immunogen
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Ezrin (phospho Tyr478) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 478 (P-V-Y (p)-E-P) derived from Human Ezrin.
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Ezrin (phospho Tyr478) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Western Blot: 1:500~1:1000:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Ezrin (phospho Tyr478) AntibodyTarget Information
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Gene Symbol
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EZR
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Alternative Names
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Cytovillin
EZRI
p81
VIL2
Villin 2
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Molecular Weight(MW)
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70 kDa
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Tissue Specificity
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The antibody detects endogenous level of Ezrin only when phosphorylated at tyrosine 478.
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Ezrin (phospho Tyr478) AntibodyDatabase Links
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Entrez Gene
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7430
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Protein Accession
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NP_001104547.1
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Ezrin (phospho Tyr478) AntibodyApplication
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Application
Western blot analysis of extracts from K562 cells treated with Na3VO4 using Phospho-Ezrin (Tyr478) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Application Notes
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Western Blot: 1:500~1:1000:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20?C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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