HSF1 Sumoylation Site Antibody
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產品名稱: HSF1 Sumoylation Site Antibody
產品型號:
產品展商: immunoclone
產品文檔: 無相關文檔
簡單介紹
HSF1 Sumoylation Site Antibody迅速增長的產品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。HSF1 Sumoylation Site Antibody嚴格的質量控制和驗證實驗包括各種不同的應用：WB、細胞**熒光、**組化、流式細胞術、ELISA、CHIP、IP和peptide array。
HSF1 Sumoylation Site Antibody
的詳細介紹
HSF1 Sumoylation Site AntibodyProduct Profile
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Product Name
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HSF1 Sumoylation Site Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Heat shock transcription factor 1 (HSF1) mediates the induction of heat shock protein gene expression in cells exposed to elevated temperature and other stress conditions. In response to stress, HSF1 acquires DNA-binding ability and localizes to nuclear stress granules. SUMO modification of HSF1 converts HSF1 to the DNA-binding form. HSF1 colocalizes with SUMO-1 in nuclear stress granules, which is prevented by mutation of the HSF1 lysine targeted for sumoylation.1) Hilgarth, et al., Biochem Biophys Res Commun. 2003 Mar 28;303(1):196-200.
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Immunogen
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This HSF1 Sumoylation Site antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-309 amino acids from human HSF1 Sumoylation Site.
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HSF1 Sumoylation Site AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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Ig
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Host Species
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Rabbit
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Tested Applications
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IFWB
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For WB starting dilution is: 1:1000 For IF starting dilution is: 1:10~50:
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Species Reactivity
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HumanMouse
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Concentration
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1mg/ml
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Purification
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Unpurified
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HSF1 Sumoylation Site AntibodyTarget Information
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Gene Symbol
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HSF1
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Alternative Names
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Heat shock factor protein 1
HSF 1
Heat shock transcription factor 1
HSTF 1
HSF1
HSTF1
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Molecular Weight(MW)
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57 kDa
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Sequence Similarities
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Predicted species reactivity based on immunogen sequence: Bovine
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HSF1 Sumoylation Site AntibodyDatabase Links
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Entrez Gene
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3297
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Protein Accession
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Q00613
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HSF1 Sumoylation Site AntibodyApplication
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Application
Western blot analysis in Jurkat cell line and mouse heart tissue lysates (35ug/lane).
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Application
Confocal immunofluorescent analysis of HSF1 Sumoylation Site Antibody with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
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Application Notes
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For WB starting dilution is: 1:1000 For IF starting dilution is: 1:10~50:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store at 4?C for three months and -20?C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Storage Buffer
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Supplied in PBS with 0.09% (W/V) sodium azide.
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