Tyrosine Hydroxylase Antibody
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產品名稱: Tyrosine Hydroxylase Antibody
產品型號:
產品展商: immunoclone
產品文檔: 無相關文檔
簡單介紹
Tyrosine Hydroxylase Antibody迅速增長的產品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Tyrosine Hydroxylase Antibody嚴格的質量控制和驗證實驗包括各種不同的應用:WB、細胞**熒光、**組化、流式細胞術、ELISA、CHIP、IP和peptide array。
Tyrosine Hydroxylase Antibody
的詳細介紹
Tyrosine Hydroxylase AntibodyProduct Profile
Product Name
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Tyrosine Hydroxylase Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001; Dunkley et al., 2004).1) Dunkley PR, Bobrovskaya L, Graham ME, Von Nagy-Felsobuki EI, Dickson PW (2004) Tyrosine hydroxylase phosphorylation: regulation and consequences. J Neurochem 91:1025-1043.
More
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Immunogen
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SDS-denatured rat tyrosine hydroxylase, purified from pheochromocytoma.
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Tyrosine Hydroxylase AntibodyKey Feature
Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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IFIHCWB
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Species Reactivity
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Mammalian species
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Tyrosine Hydroxylase AntibodyTarget Information
Gene Symbol
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Th
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Alternative Names
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The
Tyrosine 3-hydroxylase
TH
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Molecular Weight(MW)
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60
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Tissue Specificity
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Specific for the ~60k tyrosine hydroxylase protein.
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Tyrosine Hydroxylase AntibodyDatabase Links
Entrez Gene
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25085
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Protein Accession
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P04177
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Tyrosine Hydroxylase AntibodyApplication
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Application
Western blot of 10 ug of rat caudate lysate showing specific immunolabeling of the ~60k TH protein.
Additional Information
Form
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Liquid
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Storage Instructions
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Tyrosine Hydroxylase antibody can be stored at -20?C and is stable at -20?C for at least 1 year.
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Storage Buffer
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100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
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