FAK (phospho Ser843) Antibody
如果您對該產品感興趣的話,可以
產品名稱: FAK (phospho Ser843) Antibody
產品型號:
產品展商: immunoclone
產品文檔: 無相關文檔
簡單介紹
FAK (phospho Ser843) Antibody迅速增長的產品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。FAK (phospho Ser843) Antibody嚴格的質量控制和驗證實驗包括各種不同的應用：WB、細胞**熒光、**組化、流式細胞術、ELISA、CHIP、IP和peptide array。
FAK (phospho Ser843) Antibody
的詳細介紹
FAK (phospho Ser843) AntibodyProduct Profile
|
Product Name
|
FAK (phospho Ser843) Antibody
|
|
Antibody Type
|
Primary Antibodies
|
|
Product description
|
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.1) Jiang X, Sinnett-Smith J, Rozengurt E (2007)Cell Signal 19, 1000-10 . Jacamo R, Jiang X, Lunn JA, Rozengurt E (2007)J Cell Physiol 210, 436-44. Le Boeuf F, Houle F, Sussman M, Huot J (2006)Mol Biol Cell 17, 3508-20 .
More
|
|
Immunogen
|
FAK (phospho Ser843) antibody was raised against a peptide sequence around phosphorylation site of serine843 (R-G-S (p)-I-D) derived from Human FAK .
|
FAK (phospho Ser843) AntibodyKey Feature
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Host Species
|
Rabbit
|
|
Tested Applications
|
WB
|
|
|
Western Blot: 1:500~1:1000:
|
|
Species Reactivity
|
HumanMouseRat
|
|
Concentration
|
1mg/ml
|
|
Purification
|
Affinity purified
|
FAK (phospho Ser843) AntibodyTarget Information
|
Gene Symbol
|
PTK2
|
|
Alternative Names
|
FADK 1
FAK1
Focal adhesion kinase 1
PTK2
pp125FAK
More
|
|
Molecular Weight(MW)
|
120 kDa
|
|
Tissue Specificity
|
The antibody detects endogenous level of FAK only when phosphorylated at serine 843.
|
FAK (phospho Ser843) AntibodyDatabase Links
|
Entrez Gene
|
5747
|
|
Protein Accession
|
NP_001186578.1
|
FAK (phospho Ser843) AntibodyApplication
-
Application
Western blot analysis of extracts from HepG2 cells treated with PMA using Phospho-FAK (Ser843) Antibody. The lane on the right is treated with the antigen-specific peptide.
|
Application Notes
|
Western Blot: 1:500~1:1000:
|
Additional Information
|
Form
|
Liquid
|
|
Storage Instructions
|
Store antibody at -20?C for up to one year.
|
|
Storage Buffer
|
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
|
