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產品名稱: Mouse Ptk2 Antibody
產品型號:
產品展商: immunoclone
產品文檔: 無相關文檔
簡單介紹
Mouse Ptk2 Antibody迅速增長的產品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。Mouse Ptk2 Antibody嚴格的質量控制和驗證實驗包括各種不同的應用：WB、細胞**熒光、**組化、流式細胞術、ELISA、CHIP、IP和peptide array。
Mouse Ptk2 Antibody
的詳細介紹
Mouse Ptk2 AntibodyProduct Profile
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Product Name
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Mouse Ptk2 Antibody
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Antibody Type
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Primary Antibodies
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Product description
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Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly (By similarity). Plays a potential role in oncogenic transformations resulting in increased kinase activity.1) Enciso, J.M., et al. Dev. Dyn. 239(10):2570-2583(2010)
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Immunogen
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This Mouse Ptk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-453 amino acids from the Central region of mouse Ptk2.
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Mouse Ptk2 AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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Ig
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Host Species
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Rabbit
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Tested Applications
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WB
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For WB starting dilution is: 1:1000:
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Species Reactivity
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Mouse
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Concentration
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1mg/ml
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Purification
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Affinity purified
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Mouse Ptk2 AntibodyTarget Information
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Gene Symbol
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Ptk2
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Alternative Names
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Focal adhesion kinase 1
FADK 1
Focal adhesion kinase-related nonkinase
FRNK
Protein-tyrosine kinase 2
p125FAK
pp125FAK
Ptk2
Fadk
Fak
Fak1
Kiaa4203
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Molecular Weight(MW)
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124 kDa
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Mouse Ptk2 AntibodyDatabase Links
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Entrez Gene
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14083
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Protein Accession
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P34152
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Mouse Ptk2 AntibodyApplication
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Application
Western blot analysis in mouse stomach tissue lysates (35ug/lane).
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Application Notes
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For WB starting dilution is: 1:1000:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store at 4?C for three months and -20?C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Storage Buffer
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Supplied in PBS with 0.09% (W/V) sodium azide.
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