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產(chǎn)品名稱: EGF Receptor Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
EGF Receptor Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細(xì)胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。EGF Receptor Antibody嚴(yán)格的質(zhì)量控制和驗證實驗包括各種不同的應(yīng)用：WB、細(xì)胞**熒光、**組化、流式細(xì)胞術(shù)、ELISA、CHIP、IP和peptide array。
EGF Receptor Antibody
的詳細(xì)介紹
EGF Receptor AntibodyProduct Profile
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Product Name
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EGF Receptor Antibody
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Antibody Type
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Primary Antibodies
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Product description
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EGFR is a transmembrane glycoprotein that is a member of a family of protein tyrosine kinases crucial in maintaining a normal balance in cell growth and development. Growth factor receptors are involved not only in promoting the proliferation of normal cells but also in the aberrant growth of many types of human tumors. For example, the epidermal growth factor receptor (EGFR) is mutated and/or overexpressed in many common solid human squamous cell carcinomas including breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. Over-expression of the EGFR gene occurs in carcinomas with and without gene amplification. EGFR and erbB-2 are particularly important in breast cancer because increased production or activation has been associated with poor prognosis. EGFR belongs to a family of growth factor receptors, which also includes ErbB-2/HER-2/neu, ErbB-3/HER-3/neu and ErbB-4/HER-4neu. EGFR can heterodimerize with each of the members of this family.
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Immunogen
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EGF Receptor antibody was raised against amino acids 1189 - 1199 of EGF Receptor (Human).
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EGF Receptor AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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ELISAIHCWB
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EGF Receptor antibody can be used in Western Blot starting at 0.5 - 4 μg/mL, immunohistochemistry starting at 5 μg/mL, and immunoprecipitation.:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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EGF Receptor AntibodyTarget Information
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Gene Symbol
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EGFR
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Alternative Names
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EGFR
EGFf receptor
ERBB
ERBB1
MENA
Panitumumab
PIG61
Proto-oncogene c-ErbB-1
V-erb-b homolog
EGF-R
HER1
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EGF Receptor AntibodyDatabase Links
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Entrez Gene
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1956
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Protein Accession
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P00533
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EGF Receptor AntibodyApplication
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Application
Immunohistochemistry staining of EGF receptor in placenta tissue using EGF receptor Antibody.
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Application Notes
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EGF Receptor antibody can be used in Western Blot starting at 0.5 - 4 μg/mL, immunohistochemistry starting at 5 μg/mL, and immunoprecipitation.:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store EGF Receptor antibody at 4 ?C or -20 ?C. As with all antibodies avoid freeze/thaw cycles.
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Storage Buffer
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0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
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